Now ranked 25th overall the Skins allow 4

Now ranked 25th overall, the Skins allow 4.4 YPC and would be severely weakened by Haynesworth's absence. McCoy is a high-end RB2 going forward.Jason Avant is a serviceable WR3 gamble if you're desperate. He has 12 catches for 182 yards and a touchdown in his last two outings, and Washington will struggle to defend the slot without Hall Rock Cartwright was this week's No 1 fantasy pickup. He has shown some quickness in the hole as Ladell Betts' "change of pace" back over the past few games, but there's a reason he's been a special teamer his entire eight-year career.The 29-year-old hasn't scored a rushing touchdown since 2005 and now faces a Philadelphia defense that ranks top ten against the run, permitting under four yards a carry.Cartwright isn't even a safe bet to operate as a true featured back with Quinton Ganther and Marcus Mason behind him Neither is a clearly inferior ball-carrying option. On paper at least, this one is a mismatch favoring Philly.My Pick- Eagles 4:05 P.M. Crabtree scored his first NFL touchdown against a tough Green Bay secondary in Week 11.He's a borderline WR2 against Jacksonville's No 25 pass defense Josh Morgan and Isaac Bruce are rotating opposite Crabtree Neither is an option. For many of the reasons above, Alex Smith is worth a long look if you're desperate for a QB1.

17 overall.Coach Mike Singletary reaffirmed this week that Gore is the 49ers' offensive centerpiece, and that they won't suddenly become a spread team. Expect a healthy 25 touches from Gore.Among TEs, only Dallas Clark has more fantasy points than Vernon Davis in 2009. The 49ers' run defense entered Week 11 allowing the fewest yards per carry in the league and as the NFL's No 3 overall unit. Minus ILB Takeo Spikes (hamstring), however, San Francisco was exposed by Ryan Grant for 145 total yards and a touchdown.Maurice Jones-Drew is a far better talent than Grant and Jags offensive coordinator Dirk Koetter likely noticed the 49ers' leaks in film study this week.If Jones-Drew's 1,862-total yard and 21-touchdown paces weren't enough to make you feel confident about him, this development should help. Check his Friday update, but he's an obvious must-start if he plays.The 49ers are playing musical chairs at corner and may bench LCB Tarell Brown for burnable veteran Dre' Bly this week.

David Garrard's matchup is also favorable and the Bay Area weather will be fair, but he always has limited upside.Garrard typically struggles on the road, and has just two multiple-touchdown games this year Torry Holt hasn't topped 37 yards since Week 6 Keep him reserved.My Pick- 49ers 4:15 P.M. ET Games Chicago Minnesota Chicago's constant protection breakdowns have gotten to Jay Cutler's head. Cutler is consistently throwing off his back foot, hurrying passes in the short-to-intermediate area, and he missed three wide-open receivers for potential TDs in last week's loss. Johnny Knox, Greg Olsen, and Devin Hester all got behind the Eagles' secondary at different points, only to be overshot.Cutler would have hit those plays in Denver with Ryan Clady on his blind side. 34-year-old Bears LT Orlando Pace is at the end of the line, however, and now has NFC sacks leader Jared Allen to deal with.